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Alumni Profiles - Dave Balkissoon

Dave Balkissoon

Dave Balkissoon
Institute for Animal Health Compton High Street Newbury, Berkshire. RG20 7NN United Kingdom
Email: dave.balkissoon@bbsrc.ac.uk
Tel: +44 (1635) 577 955
Fax: +44 (1635) 577 263

 

Profile

I received my D.V.M. in 1999 from the School of Veterinary Medicine, U.W.I. After graduation I worked in a mixed practice in Trinidad, before moving to southern Morocco in 2001 to take up an appointment with the Prince Sultan bin Abdul Aziz al Saud Foundation for the Conservation and Development of Wildlife. This wildlife facility led the world in the artificial breeding and release of their flagship species- the houbara bustard. Through the kind sponsorship of our patron, we were able to set up a world class avian veterinary diagnostic laboratory to service similar breeding centres in the wider Middle-East.

I completed an internship in raptor medicine in Dubai, United Arab Emirates, before moving to Abu Dhabi in 2003, and was one of a team of veterinary surgeons working at the world’s largest bird-of-prey hospital. The appointment involved clinical work as well as the preservation of the cultural traditions in the art of falconry and raptor conservation.

I am presently funded by the Cambridge Infectious Diseases Consortium (C.I.D.C., Dept. of Veterinary Medicine, Univ. of Cambridge) to pursue research in avian molecular immunology at the Institute for Animal Health, Compton, Berkshire. I work on the Mx gene in the chicken, and its role in antiviral action against high pathogenicity avian influenza (HPAI). I investigate Mx polymorphisms in the genotypes of highly inbred lines and ancestral breeds of chicken, and relate this to in-vitro antiviral action. I am also interested in visualizing the Mx protein interactions within the cell, in the presence of avian influenza virus. By identifying genotypes that better resist infection and pathology, breeding strategies may be employed to reduce the reservoirs to human infection. I believe the definitive establishment of the role of the Mx gene in the chicken will further inform us as to the contribution of innate immunity of birds in combating HPAI.


 

 

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